Research into conolidine has resulted in discovery of an opioid receptor in the human body called ACKR3/CXCR7. ACKR3 seems to be by far the most popular target for conolidine, which also disregards another 4 classical opioid receptors(three). thanks.. A: There is proscribed info on contraindications between Conolidine and blood https://www.proleviate.com/post/conolidine-an-alternative-natural-pain-relief-to-replace-traditional-painkillers